Revolax Sub-Q side effects are an important area of knowledge for every trained aesthetic professional using volumizing dermal fillers. As one of the most robust products in the Revolax line, Sub-Q is designed for deep tissue augmentation and structural contouring. While clinically effective, its depth of placement and concentration call for precise technique and full awareness of potential risks.
This article outlines evidence-based insights into the safety profile, adverse event management, and injection protocols related to Revolax™ SUB-Q with Lidocaine (24 mg/ml HA + 3 mg/ml lidocaine, 1.1 ml prefilled syringe).
What Is REVOLAX™ SUB-Q with Lidocaine?
REVOLAX™ SUB-Q is the densest and most viscous product in the REVOLAX range. It is ideal for:
- Chin enhancement
- Jawline contouring
- Cheekbone projection
- Deep supraperiosteal volumization
Composition:
- 24 mg/ml high-purity hyaluronic acid
- 3 mg/ml lidocaine
- 1.1 ml prefilled syringe
Manufacturer: Across Co. Ltd. (South Korea)
CE Class III certified for EU use.
More info: https://revolax.com

Common and Rare Side Effects of Revolax Sub-Q
Due to its depth and density, Sub-Q has a different risk profile compared to softer fillers. Proper planning and anatomical knowledge reduce the likelihood of complications.
Table 1: Side Effects and Incidence
Side Effect | Frequency | Notes |
---|---|---|
Swelling/redness | Common | Usually resolves in 3–5 days |
Bruising | Common | Cannula use may reduce incidence |
Tenderness | Common | Especially in chin or jawline areas |
Lumps or nodules | Uncommon | Technique-dependent; can be massaged |
Vascular occlusion | Rare | High-risk zones require aspiration & care |
Prolonged edema | Rare | Monitor closely, especially in first-time users |
How Safe Is REVOLAX™ SUB-Q in Clinical Use?
- Highly purified monophasic HA gel
- High viscoelasticity and cohesiveness
- Low migration and excellent volume retention
Clinical studies and practitioner reports show a low complication rate when proper technique and patient selection are applied. SUB-Q’s firmness makes it a powerful tool in expert hands, not suitable for superficial placement.
Injection Protocols and Prevention of Adverse Events
Table 2: Clinical Best Practices
Protocol Element | Recommendation |
Injection plane | Deep subcutaneous or supraperiosteal |
Preferred tool | Cannula 22–25G (especially in the chin/jawline) |
Maximum volume | 1.0–1.1 ml per session in a given area |
Speed | Slow, controlled injection |
Safety technique | Aspiration before bolus injections |
Post-care | Avoid pressure or manipulation for 48 hours |
Managing Revolax Sub-Q Side Effects
Even with best practices, occasional side effects require clinical management:
- Bruising/Swelling: Cold compress, arnica, patient reassurance
- Lumps: Gentle massage; if persistent, consider hyaluronidase
- Prolonged swelling: Anti-inflammatory protocol or medical evaluation
- Vascular compromise: Hyaluronidase, warm compress, urgent protocol
Reference: https://doi.org/10.2147/CCID.S80446
Combining Revolax SUB-Q with Other Treatments
Timing is crucial when integrating SUB-Q into broader treatment plans.
Table 3: Combination Timing
Other Procedure | Safe Timing Relative to SUB-Q Filler |
Botulinum toxin | 1 week before or after |
RF/microneedling | 2 weeks before or 3–4 weeks after |
Laser resurfacing | Minimum 3 weeks post-injection |
Threads or PDO lifting | Use at separate sessions or space by 4 weeks |
Post-Treatment Advice for Patients
- Do not apply makeup for 12 hours
- Avoid alcohol, heat, or exercise for 48 hours
- Refrain from touching or pressing on the treated area
- Follow-up in 1–2 weeks for evaluation
Printed aftercare guidelines are highly recommended for patient compliance.
Summary: Is Revolax Sub-Q Safe?
Property | Details |
HA concentration | 24 mg/ml |
Lidocaine content | 3 mg/ml |
Target area | Chin, jawline, cheeks |
Duration | Up to 12–18 months |
CE certification | Yes (Class III) |
Vascular risk | Low with cannula; avoid bolus in danger zones |
Final Notes for Medical Professionals
REVOLAX™ SUB-Q is a powerful and reliable filler when used correctly. Due to its structural nature, it is ideal for deep volumizing but requires:
- Deep anatomical understanding
- Careful patient selection
- Strict aseptic protocol
- Conservative dosing and aspirational technique
Its side effect profile is favorable in trained hands. Always educate patients clearly, and stay updated with complication management standards.
References and Resources
- Manufacturer: https://revolax.com
- Clinical Guide on Adverse Events: https://doi.org/10.2147/CCID.S80446
- Across Co. Ltd. Product Documentation
- ISAPS Safety Guidelines (2023)
- AMWC Best Injection Practices (2022)