In aesthetic medicine, midface volume loss is one of the earliest and most noticeable signs of aging. Restylane Lyft®, a hyaluronic acid-based dermal filler by Galderma, is specifically formulated to restore structure, lift, and volume in the cheeks and midface area. Known for its high G’ (elasticity) and viscosity, it provides deep tissue support while maintaining natural expression.
This professional guide presents a comprehensive overview of the use of Restylane Lyft for facial contouring, including clinical indications, injection techniques, safety protocols, and anatomical considerations, supported by scientific references and practical experience.
Chapter 1: What is Restylane Lyft?
- Composition: Crosslinked hyaluronic acid (20 mg/mL) with 0.3% lidocaine.
- Technology: NASHA™ (Non-Animal Stabilized Hyaluronic Acid), optimized for deep volumization.
- Indications:
- Cheek augmentation
- Midface volumization
- Nasolabial fold correction
- Jawline definition
Chapter 2: Ideal Patient Profile
- Adults over 30 with midface volume loss or flattened cheekbones
- Patients seeking natural lifting effect without surgery
- No active skin infection or known hypersensitivity to HA products
Chapter 3: Anatomy Considerations for Midface Injections
| Layer | Landmark Zones | Risk Areas |
|---|---|---|
| Supraperiosteal | Malar eminence, zygomatic arch | Infraorbital foramen |
| Subcutaneous | Nasolabial folds | Facial artery, infraorbital nerve |
Chapter 4: Injection Techniques
- Cannula vs. Needle: 25G cannula preferred for safety and reduced bruising; 27G needle for precision.
- Techniques:
- Bolus on periosteum
- Fanning or linear threading in subcutaneous plane
- Volume Recommendations:
- Mild correction: 0.5 ml per side
- Moderate: 1 ml per side
- Severe: up to 1.5 ml per side, divided in sessions
Chapter 5: Safety Guidelines
- Contraindications: Autoimmune diseases, bleeding disorders, allergy to lidocaine or HA
- Adverse Events:
- Common: swelling, tenderness, bruising
- Rare: vascular occlusion, nodules
- Prevention: Aspiration, slow injection, proper plane
Chapter 6: Clinical Evidence and Efficacy
- Clinical trials show effects lasting up to 12 months
- High patient satisfaction in cheek projection and midface lift
- Minimal downtime compared to surgical lifts
Chapter 7: Comparison with Similar Fillers
| Product | G’ Value | Duration | Best Use Case |
| Restylane Lyft | High | 10-12 mo | Cheeks, jawline, nasolabial folds |
| Juvederm Voluma | Moderate | 12-18 mo | Cheek projection |
| Teosyal RHA 4 | Medium | 6-12 mo | Dynamic facial zones |
Chapter 8: Case Study Example
Patient: Male, 45 y/o, visible midface flattening Treatment: 2 ml Restylane Lyft total (1 ml per side) Technique: Supraperiosteal bolus with 27G needle Outcome: Immediate lift, improved cheek contour, no complications
Chapter 9: Post-Treatment Protocol
- No massage or facial treatments for 48h
- Avoid high-heat exposure (sauna, sun)
- Review at 2-week mark for touch-up
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References
- Galderma Official Website: https://www.galderma.com
- FDA Approval Data for Restylane Lyft: https://www.accessdata.fda.gov
- American Society for Dermatologic Surgery (ASDS): https://www.asds.net
- Sundaram H et al. (2015) Aesthetic Plast Surg. “Use of HA Fillers in the Midface: Long-Term Results”
- Glogau RG, Kane MA. (2017) “Midface Volume Loss: Multimodal Approach to Treatment”